Protein–Ligand Interactions: Thermodynamic Effects Associated with Increasing Nonpolar Surface Area
نویسندگان
چکیده
منابع مشابه
Effects of nonpolar solutes on the thermodynamic response functions of aqueous mixtures.
We investigate the effect of adding nonpolar solutes at atmospheric pressure on water's temperature of maximum density, isothermal compressibility, and isobaric heat capacity, using a statistical mechanical model of water solutions [H. S. Ashbaugh, T. M. Truskett, and P. G. Debenedetti, J. Chem. Phys. 116, 2907 (2002)]. We find that the temperature of maximum density increases with solute hydro...
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ژورنال
عنوان ژورنال: Journal of the American Chemical Society
سال: 2011
ISSN: 0002-7863,1520-5126
DOI: 10.1021/ja2068752